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Related to gross tumor volume: Clinical Target Volume
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Regions of interest (ROIs) were drawn manually around the gross tumor volume by a radiation oncologist experienced in treatment of lung carcinoma, and healthy structures such as the heart, liver, spleen, trapezius muscle, descending aorta, fat, sternum, spinal cord, and vertebral bodies were contoured afterwards by a graduate student.
Results showed that PET imaging increased the estimation of the gross tumor volume by 22-28% and are highly valuable for defining the target volume for the nano cancer therapy.
For RT planning, MRI is extremely useful to delineate the gross tumor volume (GTV), both within and beyond the bone.
(2) The gross tumor volume (GTV) includes the known disease as determined by physical examination, imaging studies, and other diagnostic information.
After CT simulation, CT images were fused with magnetic resonance imaging (MRI) or positron emission tomography-CT images to contour the gross tumor volume and the organs.[sup][20],[21] Prior to 2012, we administered conventional radiotherapy (CRT) at doses ranging from 40 to 50 Gy across 20 to 25 fractions.