Oki et al., "Hair cycle
resting phase is regulated by cyclic epithelial FGF18 signaling," Journal of Investigative Dermatology, vol.
In the current study, it was demonstrated that selecting functional factors in deer antler may play an important role in regulating the hair cycle
and promoting hair cell proliferation in rodents.
We have a hair cycle
, which means it grows, rests, and sheds.
Normally, the hair cycle
continues throughout a person's life.
Thus, MT, IGF-1, and FGF5 act as regulators of hair growth by cell proliferation and transformation of hair cycle
, but the underlying mechanisms are still unknown.
To induce synchronized hair cycle
, the hairs on the dorsal skin of 7-week-old mice were depilated as previously described [36, 37].
During the adult hair cycle
, HFSCs periodically go through phases of activation and quiescence to maintain a stem cell population and to produce new hair follicles.
Alopecia areata (AA) is a disease characterized by hair cycle
dysfunction and the presence of peribulbar and perifollicular mononuclear cell infiltrate.1 The majority of patients report the rapid onset of one or several well-defined, usually round, 1 to 4 cm areas of scalp hair loss.
With the average person shedding between 20-50 strands of hair a day as each hair goes through its very own hair cycle
, losing some hair is perfectly normal.
Exsymol; and Targeting Outer Root Sheath Stem Cells and Dermal Papilla Fibroblasts to Reactivate the Hair Cycle
, Fabrice LeFevre, Ph.D., Induchem Inc.
(24) AA causes a disturbance in the normal dynamics of the hair cycle
. Anagen follicles are precipitated into telogen.
It was also argued that, since stem cells required protection against apoptotic hair cycle
, investigating apoptosis-suppressing Bcl-2 protein together with the absence of the apoptosis-promoting Bax would be another reliable method by which the investigators could look for the presence of stem cells 6].