We therefore used the PE reads of the donor- and recipient-specific alleles to determine the size distribution of plasma DNA molecules derived from the liver and the hematopoietic system
A value of V =6 (central estimate) is used for life-threatening damage to the hematopoietic system
The result shows the impact of irradiation on the hematopoietic system
in this animal model.
Umbilical cord blood engrafted and successfully reconstituted the hematopoietic system
in 90% of the study patients, Laughlin and colleagues noted.
These nonhematopoietic cells accounted for only a minority of the free circulating DNA, agreeing with our previous findings that the hematopoietic system
is the predominant origin of plasma cell-free DNA (2).
However, in these male patients, the hematopoietic system
was predominantly, and in many cases close to 100%, converted into female after transplantation (Table 1).
Subsequently, we intend to describe how aged induced disorders of BM stroma ultimately control HSPC maintenance and perturb the homeostatic regulation of the hematopoietic system
Components of the Hematopoietic System
that can be Leveraged for Cancer Cellular Therapy
The recipient mice developed durable mixed chimerism, where the hematopoietic system
is a mixture of donor and recipient cells.
These are used to treat diseases of the immune system or hematopoietic system
These cells are used to reconstitute the hematopoietic system
of patients afflicted with hematologic malignancies, like leukemia and lymphoma, and more than 70 genetic diseases.
The Journal is dedicated to communication and objective analysis of developments in the biology, characteristics, and therapeutic utility of stem cells, especially those of the hematopoietic system