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Related to hemolytic crisis: sequestration crisis, aplastic crisis
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We describe the management of a pregnant patient with two life-threatening complications of sickle cell anemia, acute chest syndrome and hemolytic crisis.
Her clinical deterioration in oxygenation and radiographic progression in the setting of a hemolytic crisis was consistent with acute chest syndrome; influenza was the likely contributory factor.
Prompt recognition of the hemolytic crisis with acute chest syndrome and initiation of critical care management and transfusion support are necessary for enhanced maternal and fetal outcome.