lesion

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Related to high-grade squamous intraepithelial lesion: HSIL

lesion

injury or loss. In the civil law jurisdictions the word is often used in the context of an ‘unfair’ loss, as where an adult takes advantage of a minor or someone purchases something for much less than it's worth.

LESION, contracts. In the civil law this term is used to signify the injury suffered, in consequence of inequality of situation, by one who does not receive a full equivalent for what he gives in a commutative contract.
     2. The remedy given for this injury, is founded on its being the effect of implied error or imposition; for in every commutative contract, equivalents are supposed to be given and received. Louis. Code, 1854. Persons of full age, however, are not allowed in point of law to object to their agreements as being injurious, unless the injury be excessive. Poth. Oblig. P. 1, c. 1, s. 1, art. 3, Sec. 4. But minors are admitted to restitution, not only against any excessive inequality, but against any inequality whatever. Poth. Oblig. P. 1, c. 1, s. 1, art. 3, Sec. 5; Louis. Code, art. 1858.
     3. Courts of chancery relieve upon terms of redemption and set aside contracts entered into by expectant heirs dealing for their expectancies, on the ground of mere inadequacy of price. 1 Vern. 167; 2 Cox, 80; 2 Cas. in Ch. 136; 1 Vern. 141; 2 Vern. 121; 2 Freem. 111; 2 Vent. 359; 2 Vern. 14; 2 Rep. in Ch. 396; 1 P. W. 312; 1 Bro. C. C. 7; 3 P. Wms. 393, n.; 2 Atk. 133; 2 Ves. 125; 1 Atk. 301; 1 Wils. 286; 1 Wils. 320; 1 Bro. P. 6. ed. Toml. 198; 1 Bro. C. C. 1; 16 Ves. 512; Sugd. on Vend. 231, n. k.; 1 Ball & B. 330; Wightw. 25; 3 Ves. & Bea. 117; 2 Swanst. R. 147, n.; Fonb. notes to the Treatise of Equity, B, 1, c. 2, s. 9. A contract cannot stand where the party has availed himself of a confidential situation, in order to obtain some selfish advantage. Note to Crowe v. Ballard. 1 Ves. jun. 125; 1 Hov. Supp. 66, 7. Note to Wharton v. May. 5 Ves. 27; 1 Hov. Supp. 378. See Catching bargain; Fraud; Sale.

References in periodicals archive ?
Cytologic features of high-grade squamous intraepithelial lesion in ThinPrep Papanicolaou test slides: comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology.
The ASCUS result persisted in 5 (3%), progressed to low-grade squamous intraepithelial lesions (LSIL) in 11 (8%), and progressed to high-grade squamous intraepithelial lesions (HSIL) in 7 (5%).
False-positive Papanicolaou (PAP) test rates in the College of American Pathologists PAP education and PAP proficiency test programs: evaluation of false-positive responses of high-grade squamous intraepithelial lesion or cancer to a negative reference diagnosis.
The significance of the Papanicolaou smear diagnosis of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion. Cancer.
(%) 5707 (2.7) 5820 (2.7) Abbreviations: ADC, adenocarcinoma; AGC, atypical glandular cells; AIS, adenocarcinoma in situ; ASC-H, atypical squamous cells, cannot exclude high grade squamous intraepithelial lesion; ASC-US, atypical squamous cells of undetermined significance; HSIL, high-grade squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.
Testing for high risk human papilloma virus in the initial follow-up of women treated for high-grade squamous intraepithelial lesions. Aust N Z J Obstet Gynaecol.
The cytological findings would be expected to encompass those cytological entities without significant patient effect (atypical squamous cells of undetermined significance [ASC-US] and low-grade squamous intraepithelial lesions [LSILs]), as well as those that may have clinical influence (high-grade squamous intraepithelial lesions [HSILs]).
ASCH would indicate cytologic changes that suggest high-grade squamous intraepithelial lesion but lack definitive criteria.
High-grade squamous intraepithelial lesion was the second most-common, abnormal Pap test result in 917 of 3649 patients (25.1%), followed by LSIL in 751 of 3649 patients (20.6%), ASC-H in 481 of 3649 patients (13.2%), and atypical glandular cells in 177 of 3649 patients (4.9%).
The 2001 Bethesda system sought to eliminate the confusion around an ASC-US diagnosis, by better defining criteria, encouraging downgrading to negative for intraepithelial lesion and malignancy (NILM) when possible, and introducing a new atypical category--atypical squamous cells of a high-grade squamous intraepithelial lesion cannot be ruled out (ASC-H).
CLIA '88 also mandates review of all Pap tests interpreted as NILM (NILM Pap tests) from the last 5 years for a patient with a current Pap test that shows a high-grade squamous intraepithelial lesion (HSIL) or carcinoma (HSIL+).