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During product and process development, Argos conducted immunopotency evaluations, which demonstrated that IL-12 is a critical factor in the induction of naove, cytolytic, antigen-specific T cells with the capacity for rapid expansion and the generation of the CD28+ effector/memory phenotype.
In a presentation entitled "Development of an Immunopotency Assay as a Release and Stability Test for a Recombinant Protective Antigen (rPA) Anthrax Vaccine," Dr.
Additionally, it has been shown that sequential rather than simultaneous delivery of inflammatory and CD40L signals can influence the immunopotency of mature dendritic cells.