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Argos Therapeutics today announced the presentation of details on the Company's dendritic cell-based immunotherapy process, Arcelis[TM], as well as new research into the potential of the cytokine IL-12 as an immunopotency marker.
During product and process development, Argos conducted immunopotency evaluations, which demonstrated that IL-12 is a critical factor in the induction of naove, cytolytic, antigen-specific T cells with the capacity for rapid expansion and the generation of the CD28+ effector/memory phenotype.
The results of this study lead us to believe that IL-12 could be an immunopotency marker, because we could determine the threshold concentration for IL-12 to induce optimal T cell responses," said Charles Nicolette, Ph.