In many cases, discovery of an episode of inadvertent TB exposure in a hospital setting occurs only after recognition of the disease in an index case
(often occurring long after the TB exposure event).
The index case
was an imported case (in a returning traveler from the Dominican Republic) in epidemiologic week 22 in the north-central zone of the capital city (Valencia) (Figure 1).
This study was conducted among household contacts of index cases
with sputum smear-positive PTB in 13 selected PHCs from 1 August 2015 to 29 February 2016.
Forty-one pediatric index cases
and 114 family members were included in this study.
Majority of index cases
belonged to the rural and urban slums of the city.
To measure improvements in response indicators and outcomes over time, data from investigations of 12 of 15 outbreaks in remote areas with illness onset dates of index cases
during July 16-November 20, 2014, were analyzed.
The duration of association of the newly diagnosed patients with the index case
could not be ascertained in this study.
The Index case
: The Index case
in this outbreak was a 21 year old female with history of drowsi-ness, high fever and fits for few hours before her admission to the hospital through Emergency.
The objectives of the trial are two-fold: to assess if the vaccine protects the contacts who were vaccinated and if vaccinating the contacts will create a buffer - or ring of protected individuals - around the index case
to prevent further spread of the infection.
b--Socio-demographic parameters: sex, age, marital status, residence, geographic origin of the index case
and geographic origin of parents, grandparents (paternal, maternal) of the index case
Definition of EoC and reference case Definition Name [right arrow] Cholecystectomy Defined by [right arrow] Primary procedures AND diagnosis Primary [right arrow] K80.1 (Calculus diagnosis of gallbladder (ICD-10) with other cholecystitis) Procedure [right arrow] 51.2 (ICD-9CM) (Cholecystectomy) Index case
Adult age (< 36), without complications, non-specific cholecystitis, laparoscopic cholecystectomy, treated as inpatient, LOS 4 days Data sources
In our index case
blisters were present in upper limb and no effect on the lower limb.