induce pain

See: mistreat
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In the survey conducted, most of the students (51.5%) prescribed Ibuprofen which is in agreement with the previous studies in which the most commonly prescribed drug was ibuprofen.6 Ibuprofen is an over-the-counter (OTC) medication with analgesic, fever reducing and anti-inflammatory effects which works by reducing hormones that induce pain and inflammation in the body.7
Moreover if the needle insertion angle is small, drugs will be easily pushed into subcutaneous tissue to induce pain. If the angle is large, drugs will be pushed into muscular layer which has rich blood capillary; edema or induration may occur after blood capillary is punctured.14,15
The increase in the levels of SAG in the spinal cord of vehicle-treated sham rats may be due to the procedures involving manipulation of deep tissues, such as muscles and adjacent connective tissue, which induce pain (3,21).
Clinical neutralization of VEGF-A with anti-VEGF-A therapies or VEGF-A receptor inhibitors induce pain [51, 52].
Rats were either stimulated electrically or treated with carrageenan to induce pain. The inflammatory responses induced by the two different treatments were compared by histological evaluation.
Currently, the most important issue to be resolved in analgesia is how soft touches induce pain relief at the molecular level.
[2] Current studies regarding KOA pain mechanism mostly focus on the following three aspects: (i) synovial inflammation: pro-inflammatory cytokines such as histamine, prostaglandins, leukotriene, neuropeptides may activate nociceptor to induce pain; (ii) ostealgia: subchondral bone and marrow vessels and nerves exposure caused by KOA articular surface cartilage denudation may also lead to pain; (iii) decreased pain threshold: chronic pain in KOA demonstrates a decreased pain threshold, which can give rise to an increased pain intensity by pain stimulation in the same intensity (hyperalgesia) and even by non-painful stimulation (allodynia).
In line with an extracellular action of CASP6, intrathecal injection of recombinant CASP6 (rCASP6) is sufficient to induce pain symptoms, such as mechanical allodynia.
Superoxide anion can also directly activate nociceptive neurons to induce pain. Interestingly, neurotransmission seems to have a role in inducing superoxide anion production considering that glutamate triggers it [48].
A Conthern Classic Series CAT 350-380 digital culture bath (cold pressor) was used to induce pain. The cold-pressor chilled a 20cm deep water-bath to two degrees Celsius ([+ or -] 1 degree).
If you commonly run 20 - 30 miles per week and suddenly up that distance to 40 - 50 miles the stresses incurred in a short space of time may induce pain. If you are looking to increase distance do so with small, gradual increments.
The volunteers then had a cream rubbed into the skin of one leg to induce pain, which was either a dummy cream or a cream that contained chilli - which caused a burning and painful sensation.