Differential diagnoses for perineal nodular induration
Differential diagnosis Histolopathological features Ischemic fasciitis (13-15) Outer fringe of mitotically active fibroblasts and occasional ganglion-like cells and small vessels surrounding a central zone of necrobiosis Cellular angofibrom (*16) Uniformly moderately cellular with plump, bland spindle cells, hyalinized round, thick and walled vessels may contain adipose tissue Angiomyofibroblastoma-like tumour Alternating hypercellular and of the male genital tract (*17) hypocellular areas with clusters of rounded, epithelioid cells around numerous small vessels Mammary type fibroblastoma (*18) Well-circumscribed, more cellular, and lacks a central zone pattern.
Acceptable cure - complete re epithelialization without any induration
The findings of this survey suggest that, in Botswana, a TST with induration [is greater than or equal to]10 mm can be attributed to TB infection rather than previous BCG vaccination.
However, in Botswana, an estimated 7% of children aged 3-60 months are HIV-positive, which would not account for the large proportion of children with an induration of zero.
The article on measurement of induration in tuberculin testing brought about some random thoughts that require clarification ("Try the Ballpoint Pen Technique to Improve Interpretation of Tuberculin Skin Test Reaction," August 2002, p.
In that event there is an area of erythema but no definite palpable border of induration can be found.
Lee regarding the need to measure the induration with a ruler or tape measure, but I wonder why the measurement of the widest diameter is the only truthful one.
With regard to an induration of 4 mm versus an induration of 5 mm, or 9 mm versus 10 mm, current protocols advise differently It all boils down to the fact that identification of risk factors is more important than 1 or 2 mm of variation in the measurements.