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Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor.
To our knowledge, whereas Cd(II) has been shown to inhibit a number of DNA repair enzymes, our studies are the first to identify a specific DNA repair protein target for lead.
AgION's technology is based on naturally-occurring silver which inhibits the growth of microorganisms such as bacteria, mold and fungus.
3+] inhibits NO synthesis by endothelial cells, we investigated the effect of [As.
Further tests showed that acetaminophen inhibits this same variant, linking the drug to the prostaglandin-making pathway.
AgION Technologies, located in Wakefield, Massachusetts, is a leader in providing customized antimicrobial solutions based on silver that continuously inhibit the growth of bacteria, mold and fungus.
OTCBB:FMVR), announced today that preclinical studies show that its compound for shingles inhibits viral infections exceptionally quickly and that when FV-100 is dosed orally, the active compound shows good dose dependent pharmacokinetics.
Though diets rich in vegetables inhibit cancer development, Talalay's group is one of the few to execute "the very difficult, nitty-gritty studies" of the mechanisms, says Lee W.
Yet tumors sometimes arise, and researchers are now finding evidence that the cells of those cancers have found ways to inhibit apoptosis, the process by which cells kill themselves (SN: 7/27/96, p.
These studies showed, for the first time, that an antisense DNA analog can inhibit bacterial growth in animal infections.
While the Japanese researchers have not yet determined the chemical mechanism by which saponins inhibit alcohol absorption, they have divided the inhibiting compounds into three classes according to their chemical structure.
ARIAD's preclinical kinase inhibitors fall into two classes: inhibitors of key mutant kinases that confer resistance to current therapies and compounds that inhibit multiple pathways associated with cancer progression, such as metastasis, angiogenesis and survival.