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The minimum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means of broth microdilution as stated in CLSI M07-A8, but with some modifications: a final concentration of 0.
tuberculosis isolates were tested for their susceptibilities to FQs, INH and RIF using standard minimum inhibitory concentration (M1C) method (18).
We have recently tested the 50% inhibitory concentration for artemether of the s769N PfATPase6 isolate that we had kept in liquid nitrogen, and it showed susceptibility.
Clinicians should familiarize themselves with the pharmacokinetic and pharmacodynamic parameters of an individual agent and its minimum inhibitory concentration to improve bacterial eradication.
The objective was to determine the impact of the minimum inhibitory concentration of AEO on the cell death rate of L.
The standard, says Paul Tulkens, a professor of pharmacology at Catholic University in Louvain, Belgium, is for manufacturers to create antibiotics that achieve a minimum inhibitory concentration (MIC), the amount of antibiotic required to inhibit growth of--but not necessarily kill--a given bacterium in vitro.
Their gonococcal isolates had a median minimum inhibitory concentration of 2 [micro]g/mL for azithromycin.
CPLA #26: Determination of the Mutant Prevention Concentration (MPC) & Minimal Inhibitory Concentration (MIC) of Gemifloxacin (GM) against Penicillin Susceptible (PS) & Resistant (PR) Clinical Isolates of Streptococcus pneumoniae (SP)
The results of the studies, a research collaboration between Sequella and Tibotec, demonstrated that the combination of SQ109 with TMC207 decreased the TMC207 minimal inhibitory concentration (MIC) by 4- to 8-fold for the etiologic agent of TB, Mycobacterium tuberculosis.
The minimum inhibitory concentration (MIC) of EEHM, antibiotics and chlorpromazine (CPZ) were determined in BHI by the microdilution assay using suspensions of 10 (5) cfu/ml and a drug concentration range of 1024 to 1 mg/ml (two-fold serial dilutions) (15).
Purified cPA (>99%) yielded typical minimal inhibitory concentration (MIC) values of 10-20 microg/ml against gram-positive bacteria.