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In many forms of epilepsy, loss or malfunction of inhibitory nerve cells within the hippocampus plays a critical role.
In another study, GABA hyperpolarized the sternal arterial valve and masked inhibitory postsynaptic potentials (IPSPs) arising from inhibitory nerve stimulation (Kuramoto et al.
High frequency EEG activity called gamma, for example, might reflect the activity of fast-spiking cells which are often a subclass of inhibitory nerve cells containing parvalbumin.

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