Only one complication was insertional
quadriceps femoris has a short muscle belly, a thin insertional
tendon, and a thin and weak patellar ligament.
effectiveness PiggyBac Elimination of Inefficient transposons insertional
excision, potential mutagenesis; no for genomic toxicity footprint upon excision; higher genome integration efficiency Protein Free of genetic Slow kinetics, low materials; direct efficiency; delivery of difficulties in reprogramming factor generation and proteins purification of reprogramming protein Small molecules Ease of handling; no More than one requirements for target, toxicity reprogramming factors Type Transgene Efficiency Ref.
Wang et al., "Insertional
oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1," The Journal of Clinical Investigation, vol.
Comparison of results of retrocalcaneal decompression for retrocalcaneal bursitis and insertional
Achilles tendinosis with calcific spur.
Needle electromyography (EMG) of left tibialis anterior and peroneus longus muscles showed increased insertional
activity, fibrillation (2+), positive sharp waves (2+) and reduced recruitment (Table 2).
Maternal whole chromosome FISH analysis detected reciprocal translocation between the p arm of chromosome 2 and q arm of chromosome 7 while there was an extra signal belonging to chromosome 7 on the long arm of chromosome 2 showing an insertional
In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional
inactivation of the PhoQ/PhoP mgrB regulator.
Eccentric loading compared with shock wave therapy for chronic insertional
(14) Ultrasound can also distinguish bony changes that can occur in the context of insertional
In the diagnostic world, this could lead to the false positive assertion that there is an insertional
(likely frameshifting) event, creating a potentially erroneous diagnosis.
This family of serine/threonine kinases was first recognized in a retroviral insertional
mutagenesis study [1, 2].