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Patients must have daily insulin injections, and they live on the balance beam between diabetic coma (too much acid in the blood from an inability to use blood sugar) and insulin shock (too much insulin taken to protect against diabetic coma).
The film compresses all of Nash's hospitalization into one where he received insulin shock therapy to the point of grand mal convulsions.
Insulin shock is a more severe condition of an insulin reaction that occurs when blood-sugar levels rapidly decrease and are not countered by some form of glucose.
Then torn up as we see Nash come apart, enduring insulin shock treatment and spells in institutions.

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