Results of intradermal tests
, done in eight patients, were positive in three and negative in five.
An intradermal test
administers the allergen into the deeper dermal layer of the skin -- rather than the surface layer.
Comparison of three prick test methods with the intradermal test
and with the rast in the diagnosis of mite allergy.
: A small amount of allergen is injected into the dermis which is heavily populated with mast cells.
The Mantoux test is known as the tuberculin intradermal test
, and it implies intradermal administration.
Serial dilution quantitative intradermal testing, also referred to as skin endpoint titration (SET), is a modified intradermal test
that uses specific antigen dilutions to establish the minimum amount of antigen required to produce a positive skin test, also referred to as the endpoint.
Immunotherapy is usually started with an intradermal test
dose of 0.05 ml from the treatment vial, followed by weekly injections escalating by 0.05 ml each time until the symptom-relieving dose (the highest dose of antigen that provides maximum relief of symptoms without producing any significant local or systemic reactions) is achieved.
These investigations are most commonly performed by skin prick and intradermal test
, although recommended procedures vary.
One patient of 15 with a family history of an anaphylactic reaction during anaesthesia had a positive intradermal test
. The records of the reaction were obtained and the adverse event was postoperative vomiting.
In cases using multiple drugs, methods, such as the oral stimulation test, skin patch test, drug lymphocyte stimulation test (DLST), intradermal tests
, and skin prick test, are used to identify the responsible drug (8).
It is documented that the negativity of intradermal tests
to other NMBAs allows for a subsequent safe use of these negative drugs.