(redirected from intranasal administration)
Also found in: Dictionary, Thesaurus, Medical, Financial, Encyclopedia.


The performance of executive duties in an institution or business. The Small Business Administration is responsible for administration of some disaster-relief loans. In government, the practical management and direction of some department or agency in the Executive Branch; in general, the entire class of public officials and employees managing the executive department. The management and distribution of the estate of a decedent performed under the supervision of the surrogate's or probate court by a person duly qualified and legally appointed. If the decedent made a valid will designating someone called an executor to handle this function, the court will issue that person letters testamentary as authority to do so. If a person dies intestate or did not name an executor in his or her will, the court will appoint an administrator and grant him or her Letters of Administration to perform the duties of administration.

An executor or administrator must carry out the responsibilities of administration, including collection and preservation of the decedent's assets; payment of debts and claims against the estate; payment of estate tax; and distribution of the balance of the estate to the decedent's heirs.


noun administratio, care, conduct, control, direction, dispensation, disposal, disposition, execution, executive charge, guardianship, handling, keeping, management, ministration, performance of executive duties, practical management, procuratio, regulation, settlement of an essate, superintendence, supervision
Associated concepts: administration of a bankrupt's estate, administration of an estate, administration of expenses, addinistration of the laws, fair administration of justice, trust administration
Foreign phrases: Nihil infra regnum subditos magis connervat in tranquilitate et concordia quam debita legum administratio.Nothing better preserves in tranquillity and concord those subjected to the same government than the due administration of the laws.
See also: act, action, agency, apportionment, authorities, bureau, bureaucracy, charge, commission, control, custody, direction, dispensation, disposition, economy, enactment, enforcement, generalship, government, guidance, management, performance, regime, regulation, supervision, transaction


1 the political executive.
2 the conduct or disposal of the estate of a deceased person.
3 the management by a trustee of an estate subject to a trust.
4 the administering of something, such as an oath or sacrament.

ADMINISTRATION, trusts. The management of the estate of an intestate, a minor, a lunatic, an habitual drunkard, or other person who is incapable of managing his own affairs, entrusted to an administrator or other trustee by authority of law. In a more confined sense, and in which it will be used in this article, administration is the management of an intestate's estate, or of the estate of a testator who, at the time administration was granted, had no executor.
     2. Administration is granted by a public officer duly authorized to delegate the trust; he is sometimes called surrogate, judge of probate, register of wills and for granting letters of administration. It is to be granted to such persons as the statutory provisions of the several states direct. In general the right of administration belongs to him who" has the right to the venue of the personalty: as if A make his will, and appoint B his executor, who dies intestate, and C is the legatee of the residue of A's estate, C has the right of administration cum testamento annexo. 2 Strange, 956; 12 Mod. 437, 306; 1 Jones, 225; 1 Croke. 201; 2 Leo. 55; 1 Vent. 217.
     3. There are several kinds of administrations, besides the usual kind which gives to the administrator the management of all the personal estate of the deceased for an unlimited time. Administration durante minore oetate, administration durante absentia, administration pendente lite, administration de bonis non, administration cum testamento annexo.

ADMINISTRATION, government. The management of the affairs of the government; this word is also applied to the persons entrusted with the management of the public affairs.

References in periodicals archive ?
Sedation and physiologic response to manual restraint after intranasal administration of midazolam in Hispaniolan Amazon parrots (Amazona ventralis).
The sedative effects of each drug after intranasal administration were subjectively evaluated based on defined criteria.
The objective of this study was to assess sedation and physiologic changes associated with intranasal midazolam (2 mg/kg) administration and intranasal administration of the antagonist, flumazenil (0.
The studies concluded that swine and bird flu vaccines using BioSante's BioVant may allow for availability of a greater number of lower-dose vaccines, due to its dose sparing characteristics, and intranasal administration could provide more convenient and wider distribution during a flu pandemic.
Thus, after intranasal administration of the vaccine, a strong immune response is stimulated that provides effective protection against the flu.
The largest potential for success of mucosal vaccine delivery lies in oral and intranasal administration, while pulmonary vaccination appears less promising due concerns regarding safety and reliable dosing.
PATANASE([R]) nasal spray is intended only for intranasal administration.
Javelin will present two posters, the first, "The Pharmacokinetics, Safety, and Tolerability of Repeat Doses of Intranasal Ketamine in Healthy Volunteers," presents the pharmacokinetic results following repeated intranasal administration of PMI-150 according to a set dosing schedule.
Efforts to be pursued at Lovelace will involve both the inhalational administration of Homspera, which was used in early radioprotection studies, as well as the intranasal administration used more recently in the studies demonstrating anti-viral activity, vaccine adjuvant activity, and hematologic stem cell.
Intranasal administration of a candidate influenza vaccine with Ampligen[R] resulted in dramatically increased secretion of IgA (also known as immunoglobulin A) which formed the basis of mucosal immunity.
The Intravail[R] and ProTek[R] technologies enable the non-invasive delivery of a broad range of protein, peptide and non-peptide macromolecular and small molecule therapeutics with exceptionally high and unmatched bioavailability, comparable in efficiency to subcutaneous injection, via the intranasal administration route.
Data showed that local intranasal administration in mice of an siRNA targeting Ang2 resulted in specific inhibition of messenger RNA (mRNA) by more than 60 percent.