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LARGE. Broad; extensive; unconfined. The opposite of strict, narrow, or confined. At large, at liberty.

A Law Dictionary, Adapted to the Constitution and Laws of the United States. By John Bouvier. Published 1856.
References in periodicals archive ?
Fate of proteins and amino acids in the small and large intestine: what consequences for the mucosa?
As predicted, the sex difference is present in acquisition (stomach, small intestine, and large intestine), distribution (lung), and expenditure (gonad) organs; however, storage organs (liver and fat bodies) did not show sex differences.
The use of EBD for the stenotic lesions of CD has been reported since the 1990s, with the procedure being conducted using an upper gastrointestinal endoscope or colonoscope mainly for the stenosis in the upper gastrointestinal tract, in the large intestine, or at the anastomotic site (17-25).
Histopathology revealed that the large intestine nodules were composed of projections of the mucosal epithelium into the submucosa, which formed tubules lined by a single layer of columnar epithelium with high cellularity (1-2 mitosis / obj.
Trillions of living organisms, including many strains of bacteria, live in your gut (small and large intestines); as a whole, they make up a community called a "microbiome." Research has shown that a balanced gut microbiome containing an adequate number of probiotics supports the health of your digestive and immune systems and lowers levels of chronic inflammation; a microbiome that's out of balance, on the other hand, can contribute to immune and inflammation-related disorders.
But when the spores reached the large intestine, where normal gut bacteria generate secondary bile acids, those secondary bile acids stopped the C.
GASTROINTESTINAL MALIGNANCIES: In the present study of gastrointestinal malignancies, maximum incidence was observed in stomach (50.6%) followed by large intestine (30.6%), esophagus (15%) and small intestine (3.6%) while esophagus (42%) followed by stomach (24%) and intestine (34%) was most commonly involved in the earlier study.
The doting mum, who has two children aged six and 11, fears she may need her large intestine removed should her steroid medication fail to improve her condition.
Pinworms (Enterobius vermicularis), meanwhile, are very thin and tiny (two to 13mm) white worms that reside in the large intestine where they feed on digested food.
The results: folic-acid takers had no higher risk of cancers of the large intestine, breast, prostate, lung, or any other site.
In 2007, she underwent surgery at Jackson Memorial hospital in Miami and was given a new liver, pancreas, stomach and small and large intestine. Five years later, she gave birth to a girl.
People with Hirschsprung disease have no nerves in parts of the large intestine, so muscles don't contract to produce regular bowel movements.

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