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Related to light chain disease: kappa light chain, LCDD
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To our knowledge, such a pattern of UPE from a patient with light chain disease has not been reported.
For optimal sensitivity, however, certainly when there is clinical suspicion of light chain disease, an immunologic technique such as IFE is needed (8).
We investigated 5 cases of light chain disease (4[lambda] and 1[kappa]), 2 of IgA (1 IgA[kappa] and 1 IgA [lambda]), 23 of IgG (14 IgG[kappa] and 9 IgG [lambda]), and 4 of IgM (2 IgM[kappa] and 2 IgM[lambda]) monoclonal paraproteins.