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Littoral cell angioma: a novel splenic vascular lesion demonstrating histiocytic differentiation.
Littoral cell angioma of the spleen: CT features with clinicopathologic comparison.
Studies have demonstrated that LCA has two subtypes with potentially malignant properties, littoral cell angiosarcoma (11) and littoral cell hemangioendothelioma.
Also, there have been cases of LCA and littoral cell angiosarcoma (11) reported to present as splenic rupture and hemoperitoneum.
28,29) The lining cells of the vascular channels show mild to moderate atypia with similar immunohistochemical staining patterns to littoral cell angioma, with positive immunostaining for endothelial and histiocytic markers.
Primary vascular neoplasms unique to the spleen: littoral cell angioma and splenic hamartoma diagnosis by fine-needle aspiration biopsy.