Injections of laboratory-grown
liver cells may keep patients with end-stage liver disease alive while they wait for a liver transplant and may also help treat inherited liver diseases, according to a report presented last month at the Experimental Biology 2000 meeting in San Diego, CA.
Deep sequencing of DNA isolated from
liver cells in the treated mice also showed that correction to the mutation was consistent with the survival results.
Bhatia and her team showed that
liver cells grown in their micro-liver system could be infected with hepatitis C for up to two weeks--enough time to potentially screen drugs or test how the virus behaves inside the cell culture.
Speaking to the media on the sidelines of the Newborn Screening Workshop organised by the HMC on Saturday, Cytonet Managing Director Wolfgang Rudinger said, "The
liver cell therapy is a new therapeutic approach which can be used for severe liver disorders.
Researchers anticipate that the ability of HepaLife's patented
liver cells in combination with its proprietary bioreactor system to remain functional for extended periods of time may provide for more efficient and flexible patient treatment options over prolonged periods of time, potentially improving patient outcomes as a result.
Gene therapy company uniQure NV (NasdaqGS:QURE) revealed on Tuesday the successful transfection of
liver cells with the porphobilinogen deaminase gene (PBGD) from an ongoing Acute Intermittent Porphyria (AIP) dose-escalation Phase I trial of of AMT-021 conducted in partnership with the AIPGENE Consortium, a pan-European collaboration.
Washington, July 28 ( ANI ): Researchers transplanted derived functional hepatocytes from human stem cells into mice suffering from acute liver injury, and found that these
liver cells functioned normally and raised survival of the treated animals.
The cutting-edge
liver cell therapy programme, to be conducted in Germany, will facilitate the treatment of children who suffer from urea cycle disorder that causes brain damage and death of many newborns and infants.
In addition, the Commercial Regulatory Authority of Lower Saxony, in agreement with the Paul-Ehrlich Institute, have granted Cytonet a manufacturing authorization on this basis, the first time ever for a
liver cell product.
Phenotypic and functional characterization of
liver cell precursors have therefore become major priorities in the fields of tissue engineering, liver support technology and gene therapy.
OTCBB:HPLF) (FWB:HL1) (WKN:500625) today announced that results from new tests of the Company's patented PICM-19
liver cells show the highest levels of important liver-specific metabolic activity key to mimicking human liver function, and further demonstrate the PICM-19's ability to perform equivalent to freshly harvested adult porcine hepatocytes, traditionally regarded the best available
liver cell source for bioartificial liver support.
a
liver cell taking part in metabolism, but in a less costly and more reliable manner.
