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Lymphatic duct obstruction is a disease having long history but the treatment remained a challenge because of high recurrence rate and lack of curative methods.
The lymphatic vessels carry lymph, cellular waste products, toxins, and pathogens to lymph nodes (filtering and infection-fighting sites) and on to the lymphatic ducts near the heart that dump the lymph into venous blood.
The exogenous pathway uses chylomicrons, which are synthesized in the gut to carry fats initially in the lymphatic ducts and eventually the circulation by way of the thoracic duct on to the tissues.