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The researchers found that most hematological malignancies showed increased FRRs for the same tumor type, with the highest FRRs for mixed cellularity Hodgkin lymphoma, lymphoblastic lymphoma, and mantle cell lymphoma (SIRs, 16.7, 15.8, and 13.3, respectively).
Specifically, the standardized incidence ratio was 10.15 for all malignancies, 7.33 for solid tumors, and 41.72 for hematologic malignancies.
The Fisher's exact was used for comparison of qualitative characteristics between hematological malignancies and solid malignancies, whereas the Mann-Whitney U test was used for comparison of quantitative parameters.
In Asian population, the incidence of skin malignancies is quite low as compared to the Western world.
The CIBI188A101 study is a Phase I clinical study conducted in China to evaluate the safety, tolerability, and efficacy of IBI188 in the treatment of patients with advanced malignancies. The primary objectives are to evaluate the safety, tolerability and phase II recommended doses of IBI188 as a monotherapy and in combination with other agents in subjects with advanced malignancy.
It is important that the overall five-year survival for second primary malignancy was lower than that of primary malignancies. (5)
Hematolymphoid malignancies top the cancers among children which constituted 26.3pc of all with 23.5pc in boys and 32.7pc in girls.
Immunosuppression is associated with an increased risk of malignancies due to impaired immunosurveillance and direct damage of host DNA (2,9).
This is a longitudinal prospective study of a cohort of patients with histologically confirmed sinonasal and nasopharyngeal malignancies managed at the Jos University Teaching Hospital a 520-bedspace tertiary referral hospital from February 2013 to January 2018.
The frequency of cold thyroid nodules and thyroid malignancies in patients from an iodine-deficient area.
Malignant neoplasms of the oral and maxillofacial region are amongst the commonest malignancies reported worldwide with significant variation seen across continents.
(2) The most frequent thyroid carcinoma is papillary thyroid carcinoma (PTC), which comprises 80% to 85% of thyroid malignancies. (3)