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Two slices metabolize into the blood sugar equivalent of eight teaspoons of table sugar.
These enzymes, which are made in the liver, break down nutrients from food and metabolize up to half of all drugs now in use.
Because of diet, genetics, and other factors, some people just metabolize drugs a lot more slowly," he says.
People without the protein may need smaller doses of the drugs it normally metabolizes, or they risk side effects, Schuetz explains.
In the test tube, bergamottin inactivates cytochrome P450 3A4, a digestive enzyme that metabolizes many drugs, ranging from antihistamines to medications for high blood pressure (SN: 5/24/97, p.
CYP2B6 metabolizes the substrates to only one product, whereas CYP3A4 is able to metabolize the substrates to multiple products, as shown for metolachlor in Figures 10 and 11.
The urine of all nine subjects contained NNL-Gluc, a substance produced when the body metabolizes and detoxifies; NNK.
The same enzyme metabolizes many drugs used to treat high blood pressure, heart arrhythmias, and depression.
Studies have shown that indole-3-carbinol (I3C), a component of many brassica vegetables (such as cabbage and broccoli), alters the way the body metabolizes estrogen -- stimulating the preferential production of a benign byproduct instead of a highly estrogenic and potentially carcinogenic one (SN: 7/3/93, p.
Lieber notes, however, that both cimetidine and ranitidine belong to a class of drugs that inhibit gastric alcohol dehydrogenase, an enzyme that metabolizes alcohol.