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If we can identify in advance patients whose tumors are likely to metastasize, it will improve our ability to individualize treatment of their disease.
This failure resulted in a missed opportunity to diagnose and treat the cancer, allowed the cancer to metastasize and become inoperable, and is directly responsible for the results observed here,'' Miller wrote.
5) It can metastasize to any location in the body, and its propensity to metastasize to unusual sites has been well documented.
The dark side of this growth factor, and others like it, is that they also boost a tumor's blood supply, thus enabling it to grow and metastasize to distant parts of the body.
A high index of suspicion must be maintained in cases of histologically benign eccrine acrospiromas for three reasons: (1) malignant transformation can occur, (2) the presence of both benign and malignant tissue can lead to afalse-negative diagnosis if only the benign component is obtained in the biopsy specimen, and (3) benign-appearing tumors can recur locally or metastasize.
If further studies are similarly encouraging, the treatment may eventually become a way to block the process by which cancer cells metastasize, or spread, to the bones.
Weidner and Folkman discovered a link between the number of capillaries in a tumor and its propensity to metastasize, or spread (SN: 1/19/91, p.
To metastasize from one part of the body to another, cancer cells must traverse their own basement membrane, hitch a ride in the bloodstream and cross another basement membrane to take up residence in a new tissue.
The relatively high possibility that nasopharyngeal carcinoma will metastasize to the parotid prompted Batsakis and Bautina to caution against too readily accepting a diagnosis of "primary undifferentiated carcinoma of nasopharyngeal type.
They found that tumor cells located far from blood vessels -- and thus from the oxygen supply -- show a greater tendency to metastasize to distant parts of the body after reoxygenation than tumor cells situated close to the blood supply.
DOE's acting general counsel, Eric Fygi, complained in a letter to the subcommittee that providing the documents requested by the subcommittee threatens "to metastasize without discrete bounds to embrace all current and future Yucca Mountain licensing proceeding matters.