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Ultrastructural evidence for direct projections from the pontine micturition center to glycine-immuno-reactive neurons in the sacral dorsal gray commissure in the cat.
Spinal cord lesions, interrupting spinal pathways between the pontine micturition center and the sacral spinal cord, are the most common cause of disordered bladder function and result in detrusor hyperreflexia.
Neurological disorders that affect modulatory centers in the brain above the pontine micturition center tend to produce detrusor overactivity with urgency, urge incontinence, and preservation of coordination between detrusor muscle and urethral sphincter mechanism.