disorder

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disorder

a disturbance of public order or peace. Its existence may trigger extended police powers.
References in periodicals archive ?
Considering that the prenatal diagnosis of monogenic disorders is still performed in a family-based setting in which a genetically confirmed proband or carrier has been identified, this method has a practical advantage that proband diagnosis, carrier detection, and noninvasive prenatal diagnosis can be accomplished efficiently with a single platform.
In addition, while the genetic conditions detected through current newborn screening programs are monogenic disorders, newborn screening may evolve to include screening for some disorders that have a multifactorial mode of determination, although screening for selected multifactorially determined conditions is controversial at the present time.
Height matters-from monogenic disorders to normal variation.
[beta]-Thalassemia (OMIM 613985) is a group of autosomal recessive monogenic disorders caused by mutations in the [beta]-globin genes (7).
We are hoping to work with BGI in larger projects that involve other genetic disorders, especially Cancer genetics, monogenic disorders and Thalassemia which has a very high incidence in the region."
Inherited dilated cardiomyopathies (DCM) are monogenic disorders caused by mutations in more than 30 genes, characterised by substantial phenotype heterogeneity.
Molecular characterization of rare monogenic disorders like MDM in the inbred Pakistani population could be the best strategy to control affected births through carrier screening, genetic counseling and prenatal diagnosis.
After the successful implementation of noninvasive prenatal testing (NIPT) [4] for common chromosome disorders (6, 7) and promising reports for clinically significant copy number variations (8-10), one of the obvious extensions to the technology is reliable and accurate testing for monogenic disorders (11).
The Thalassemias are common monogenic disorders of hemoglobin synthesis.
Advances in recombinant DNA technology have opened up many new diagnostic tools for monogenic disorders. DNA based techniques are also being used in the diagnosis of infectious diseases, and diagnosis and prognostication of cancers.
Monogenic disorders are more straightforward in terms of testing because the genetic defect (pathogenic mutation) in a single gene is the direct cause of the disorder.
Peter Ray provides insight into the relationship between pharmacogenetic testing and genetic testing for monogenic disorders. The new chapter on haplotyping provides an easy-to-understand description of the concept of haplotype and of how knowledge from the recently completed Hap-Map program will impact the field of pharmacogenetics.