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MONOMANIA. med. jur. Insanity only upon a particular subject; and with a single delusion of the mind.
     2. The most simple form of this disorder is that in which the patient has imbibed some single notion, contrary to common sense and to his own experience, and which seems, and no doubt really is, dependent on errors of sensation. It is supposed the mind in other respects retains its intellectual powers. In order to avoid any civil act done, or criminal responsibility incurred, it must manifestly appear that the act in question was the effect of monomania. Cyclop. Pract. Medicine, title Soundness and Unsoundness of Mind; Dr. Ray on Insanity, Sec. 203; 13 Ves. 89; 3 Bro. C. C. 444; 1 Addams' R. 283; Hagg. R. 18; 2 Addams' R. 102; 2 Addams' R. 79, 94, 209; 5 Car. & P. 168; Dr. Burrows on Insanity, 484, 485. Vide Delusion; Mania; and Trebuchet, Jur. de la Med. 55 to 58.

A Law Dictionary, Adapted to the Constitution and Laws of the United States. By John Bouvier. Published 1856.
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A este ultimo tipo de locuras, Esquirol, fiel alumno de Pinel, lo llamo "monomanias" (del griego mono, "uno" y mania, "locura").
Deleuze and Guattari conclude the discussion of the second danger by saying that, "Instead of great paranoid fear, we find ourselves taken [pris] into a thousand little monomanias, taken into things that are obvious and into clarities that surge forth from each [soul: they use their technical term here, "black hole"], and which do not form a system." (34) One can see how close the danger is to the saving: "a thousand monomanias" versus "a thousand little sexes" and of course versus "a thousand plateaus." But here too we must see that the monomanias that take us in result from the powerlessness to resist being taken in, in a powerlessness not to continue to augment and mutate.
With a generosity and humility too rare in our era of monologues and monomanias, he has entered into a wholehearted dialogue with thinkers of every philosophical orientation.