The choice of bulk olfactory mucosa rather than purified olfactory ensheathing cells or stem cells as an autograft may lead to the development of a mass containing functional respiratory
mucosal cells.
The effect was attributed to enhancement of defensive mucosal factors like mucin secretion, life span of
mucosal cells and anti-oxidant effects rather than on the offensive mucosal factors like acid and pepsin secretion.
Furthermore, there is ample evidence that friendly flora enhance the integrity of
mucosal cells by fortifying intercellular tight junctions, thereby preventing compromises in permeability.
These biochemical changes lead to nutritional shortages for colon and, to a lesser extent, small intestinal
mucosal cells, as well as increased levels of bile acids (increasing the risk for colon cancer) and estrogen (possibly increasing the risk of breast cancer).
Also, the
mucosal cells of the small intestine frequently become edematous with malnutrition, thus reducing absorptive capacity.
These side effects have been associated with the inhibition of the enzyme known as cyclooxygenase as well as other NSAID mechanisms that have a direct cytotoxic effect on gastric
mucosal cells.
AIMS AND OBJECTIVES: To study clinico-pathological & cytological changes in oral
mucosal cells of patients with the habit of smoking tobacco by using exfoliative cytology and PAP stain and comparing it with control non-smoker group.
Head & neck tumors can be detected using micro satellite analysis of DNA derived from exfoliated oral
mucosal cells samples from saliva.
Further study showed that the ability to build the thin, but important, layer of
mucosal cells was hindered by faulty FAS.
Welch says that interlaced processes may explain why inulin boosts iron absorption during digestion: "The beneficial bacteria that ferment inulin in the colon release short-chain fatty acids that increase digestive acidity, and that causes
mucosal cells to proliferate.
