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PDHc is a multienzyme complex localized in the inner mitochondrial membrane.
The long-chain forms of hydratase, LCHAD, and the 3-ketoacyl-CoA thiolase exist as a multienzyme complex located in the inner mitochondrial membrane that is called the mitochondrial trifunctional protein (MTFP) (3, 4).
Mitochondrial DNA (mtDNA) [4] replication is a complex process involving >20 proteins organized along the inner mitochondrial membrane as a multienzyme complex called the mtDNA replisome, or replication factory (1-3).

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