regeneration

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Fibroblasts synthetize collagen I and collagen III at different ratios during muscle regeneration. Cultured fibroblasts secrete and deposit collagen VI with beneficial effects on muscle stiffness.
Lynch, "Comparative evaluation of IGF-I gene transfer and IGF-I protein administration for enhancing skeletal muscle regeneration after injury," Gene Therapy, vol.
[IL-6.sup.-/-] macrophages are associated with a decrease in myoblast proliferation and muscle regeneration in vivo and it is intriguing to suggest the reduced G-CSF production is contributing to this response.
Function during Muscle Regeneration and Myogenesis In Vitro
(2004) Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo.
Myogenic differentiation was assessed by myogenin and myosin heavy chain expression and multinucleated myotube formation in vitro; skeletal muscle regeneration was tested using an in vivo mouse model with experimental glycerol myopathy.
As long as the scar persists, complete muscle regeneration is not possible.
The spliced isoforms of MNF termed as MNF-[alpha] and MNFP (Garry et al., 1997; Yang et al., 1997; 2000) which are expressed during myogenesis and during muscle regeneration. MNF-[beta] is principally expressed in quiescent satellite cells while MNF-[alpha] predominates in proliferating satellite cells after muscle injury.
Patients with end-stage renal disease are known to have myopathy with muscle regeneration [34], and here we have demonstrated cTnT expression by regenerating skeletal muscle.
Muscle regeneration might theoretically be promoted by hormones that stimulate protein production, such as growth hormone, or by anabolic steroids, which promote both protein synthesis and muscle repair.
Citation: Mark Juhas et al., Incorporation of macrophages into engineered skeletal muscle enables enhanced muscle regeneration. Nature Biomedical Engineering, 2018; DOI: 10.1038/s41551-018-0290-2
We showed that this leads to much less efficient muscle regeneration, with thinner muscle fibres, after injury.