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LCX at its origin has characteristics intermediate between elastic and muscular arteries; as a clue to its elastic nature, it has thickest tunica media and relatively thick tunica intima and behaves as a muscular artery due to having a relatively thicker tunica adventitia.
The MCA is a muscular artery and muscular arteries generally have the same basic composition as elastic arteries but the elastic tissue is reduced to a well-defined, fenestrated elastic sheet, the internal elastic lamina, in the tunica intima, and a diffuse external elastic lamina in the tunica adventitia.
As a muscular artery from the forearm, the RA has a prominent medial layer and elevated vasoreactivity, which results in a lower patency rate than that of IMA grafts.