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The process of myelin sheath formation (called myelination) requires extraordinarily high levels of lipid (fat) synthesis because most of myelin is composed of lipids, according to Dasgupta.
Research Fellow Dr Samuel Wharton said: "While most MRI-based research focuses on tissue measurements at the millimeter length scale, our experimental scans on healthy human volunteers and modeling of the myelin sheath shows that much more detailed microscopic information relating to the size and direction of nerve fibers can be generated using fairly simple imaging techniques.
The myelin sheath that surrounds nerve fibers in the brain and spinal cord is damaged by repeated immune attacks in MS.
According to the researchers, studies indicate that defects in myelin sheath regeneration can be at least partly corrected by surgically introducing cells found in the blood of younger mice into the spinal cords of older mice.
It occurs when the protective coating, known as the myelin sheath, around nerve fibres in the brain and spinal cord begins to break down, slowing the brain's communication with the rest of the body.
myelin sheath A whitish material that surrounds and insulates the fibers of nerve cells.
MS, a chronic disease of the nervous system, affects the brain and spinal cord by damaging the myelin sheath, which surrounds and protects nerve cells.
Finally, a constant, but often overlooked, feature of the active MS lesion is a variable, but often dramatic reduction in the number of oligodendrocytes,7 whose extended plasma membranes constitute the myelin sheath.
But it may also be speculated that late reabsorption of prilocain if it was injected within the myelin sheath or immediate healing of a small reversible injury of the neuronal fibers might have been the reasons.
The stem cells developed into immune cells that did not see the myelin sheath as alien, and therefore did not attack it.
The causes are not known for sure, the likeliest being a breakdown in the protective myelin sheath around the nerve allowing abnormal transmission of pain impulses to the brain.
In the brain, there is a loss of the protective myelin sheath from around the neurones.