Expansion of an unstable DNA region and phenotypic variation in myotonic dystrophy
The report assesses Myotonic Dystrophy
therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type
Endocrine function over time in patients with myotonic dystrophy
Personality patterns in patients with myotonic dystrophy
Founder effect and the prevalence of myotonic dystrophy
in South Africans: Molecular studies.
Pelargonio G, Dello Russo A, Sanna T, De Martino G, Bellocci F Myotonic dystrophy
and the heart.
The project is being supported by Blaydon MP Dave Anderson, who lost his sister, brother, niece and nephew to myotonic dystrophy
, with several other members of his family living with the effects of the condition.
Professor Muntoni informed that preclinical studies in myotonic dystrophy
are also rapidly advancing, followed by also attempts to utilise antisense oligomers in other, less common muscular dystrophy variants, for example in LGMD2B.
Heading this collection are short communications on considering myotonic dystrophy
as a "repeat disease" and using one or two individual organisms to address population-wide genetic questions.
Effects of high resistance training in patients with myotonic dystrophy
Keywords: myotonia congenita, myotonic dystrophy
, Becker myotonia, chloride channelopathy, SSCP.