IBT is currently developing the drug candidate IBP-9414, for the prevention of
necrotizing enterocolitis ('NEC') and improvement of so called feeding tolerance in premature infants.
Necrotizing enterocolitis. N Engl J Med 2011; 364(3): 255-64.
However, the risk of occurrence of
necrotizing enterocolitis was higher in this group of infants (4).
Pierro, "National prospective surveillance study of
necrotizing enterocolitis in neonatal intensive care units," Journal of Pediatric Surgery, vol.
Bush et al., "
Necrotizing enterocolitis in neonates with congenital heart disease: risk factors and outcomes," Pediatrics, vol.
Lepage et al., "Nutritional strategies and gut microbiota composition as risk factors for
necrotizing enterocolitis in very-preterm infants," American Journal of Clinical Nutrition, vol.
Occult blood in stools and
necrotizing enterocolitis. Is there a relationship?
Probiotics and
necrotizing enterocolitis. Clin Perinatol 2014; 41(4):967-978.
In Norway, a consensus-based protocol recommending prophylactic probiotic supplementation for preterm infants at highest risk for
necrotizing enterocolitis (gestational age <28 weeks, birthweight <1,000 g) was introduced in 2014.
LOW-COST, LOW-RISK interventions can significantly lower the rate of
necrotizing enterocolitis among very-low-birth-weight (VLBW) infants, according to a study published in Pediatrics.
cerebral palsy,
Necrotizing enterocolitis [where the lining of the intestinal wall dies], retinopathy of Prematurity [ abnormal blood vessel growth in the retina], hydrocephalus, and many other serious complications," explained his parents in a YouTube post.