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In addition, experience with stimulation through nerve cuff electrodes in subjects with amputation suggests that small modulation of the amplitude or width of the pulses during stimulation trains provides a more natural sensation [12].
Selective stimulation of functional muscle groups is therefore possible with a single nerve cuff electrode and may improve ankle control for standing and walking functions.
The NIH grant is designed to optimize the location of contacts within an electrode that encircle the target nerve, called a nerve cuff electrode.