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BASE. Something low; inferior. This word is frequently used in composition; as base court, base estate, base fee, &c.

A Law Dictionary, Adapted to the Constitution and Laws of the United States. By John Bouvier. Published 1856.
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Classical bioisosterism can exists among pyrimidine nitrogenous bases (single ring structure) like cytosine and uracil.
* the features that describe the nitrogenous bases as categorical effects (complimentary pairs as the base pairs, similar pairs as pyrimidines and purines, chiral pairs as the right and left twist of the helix, polar pairs as the bonding arrangements), and
Unlike DNA, which is double stranded and consists of the four nitrogenous bases A, T, G and C, RNA is single stranded and has the nitrogenous base uracil ("U") instead of thymine ("T").
The reader is probably aware that there are four such subparts, and that each of the four consists of a heterocyclic nitrogen-containing molecule (the nitrogenous base, or just "base," in context); the base covalently linked to a 5 carbon sugar (2'--deoxyribose), with the base plus sugar being referred to as a "nucleoside"; and the nucleoside with the covalent addition of one, two, or three phosphate groups to the 5' carbon, which respectively make up a nucleoside mono-, di-, or triphosphate (collectively referred to as a "nucleotide").