BW: burn wound; SOB: simple ointment base
; MRSA: methicillin-resistant S.
Group I was kept untreated and considered as negative control while Group II was treated with ointment base
only and considered as placebo (vehicle) control.
- Group 2: wounds treated topically with a simple ointment base
The stability of creams, which are generally oil in water emulsions are much more prone to microbial contamination as the continuous aqueous phase is a much more favorable medium for growth than the fatty continuous phase of an ointment base
. Therefore the in-use shelf-life of creams could be shorter than that for ointments even if a preservative is present.
However, moisturizers in an ointment base
are usually more effective.
Yissum subsequently applied to the UK Patent Office for an SPC for calcitriol either solely for calcitriol or alternatively for a combination of calcitriol with an ointment base