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I speculate, based on treating hundreds of patients who have been on Suboxone maintenance, that when Suboxone is given long-term it causes abnormal adaptations to opiate receptors and other brain receptors.
The usual physiological role of the kappa opiate receptor is not completely understood.
However, as described above, these changes would be sensitive to blocking by opiate receptor antagonists.
As a doctoral student at Johns Hopkins University she was researching the possibility that an opiate receptor existed.
Researchers at the University of Illinois at Chicago and the National Institutes of Health Center for Botanical Dietary Supplements Research may have figured out what makes the natural herb black cohosh relieve menopausal symptoms such as hot flashes - it appears to act on human opiate receptors, which play a role in regulating a body's temperature.
Currently, the most common treatment of opioid-induced respiratory depression is to administer an opiate receptor antagonist such as naloxone.
Candace Pert, PhD, was recognized for her research in discovering the opiate receptor as well as many other peptide receptors in the brain and in the body.
Morphine, heroin, fentanyl, and other powerful opiate receptor agonists have long been used for pain reduction (Brunton et al.
We were saying that taking a medication such as buprenorphine that works at the opiate receptor is what causes people to have a different kind of recovery.
Evans of the University of California, Los Angeles, and his colleagues finally obtained a detailed picture of one type of opiate receptor.
The Company's research and development pipeline includes: ADL5945 and ADL7445, novel mu opiate receptor antagonists undergoing clinical development for chronic OIC; and several earlier-stage compounds under development for the management of pain and CNS disorders.