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Related to orphan viruses: Respiratory Enteric Orphan Virus
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However, gaps in campaign performance and surveillance, evidenced by the persistence of continually missed children and the detection of wild viruses in environmental samples and orphan viruses isolated from cases and environmental samples are indicative of ongoing program challenges.
They are designated as orphan viruses, and more than half of the adult population possess antibodies directed against reoviruses, which suggests that infection occurs frequently without any specific effect on human health.
Three cases in 2014 were caused by orphan viruses, including one case of indigenous Afghanistan WPV, suggesting ongoing, undetected, low-level transmission and gaps in surveillance (10).