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11] The pathogenesis of abdominal pain remains unknown, although several possibilities have been suggested, such as ductal hypertension due to strictures or calculi, inflammation and scarring around the pancreatic nerves, alterations of the perineural sheath, pseudocysts, acute inflammation, cell-mediated cytotoxicity, and fat necrosis.
Costa J, Benign epithelial inclusions in pancreatic nerves.