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Ester-linked LAs are most often linked to true anaphylaxis, usually due to a sensitivity to their metabolite, para-aminobenzoic acid (PABA), and do not result in cross-allergy to amides.
Para-aminobenzoic acid (PABA) is an isomeric form of amino benzoic acid (ABA) that is often thought as only an ingredient used in sunscreens preparations since it can help protect the skin against ultra-violet radiation, while it is in actual fact a nutritional ingredient as well [1, 2].