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Effect of nalbuphine and pentazocine on attenuation of hemodynamic changes during laryngoscopy and endotracheal intubation: a clinical study.
For example, morphine and fentanyl are strong agonists, pethidine (meperidine) is a weak agonist, buprenorphine is a partial agonist, naloxone is an antagonist and pentazocine is a mixed agonist and antagonist.
John's wort), imipramine, MDMA, meperidine, nefazodone, nortriptyline, paroxetine, protriptyline, sertraline, tramadol, trazodone, venlafaxine Drugs that decrease Isocarboxazid, linezolid, phenelzine, 5-HT metabolism selegiline, tranylcypromine Drugs that are direct Almotriptan, buspirone, dihydroergotamine, 5-HT agonists eletriptan, frovatriptan, LSD, naratriptan, rizatriptan, sumatriptan, zolmitriptan Others L-tryptophan, carbamazepine, carisoprodol, droperidol, levodopa, lithium, metoclopramide, pentazocine, phenylpropanolamine 5-HT: serotonin; LSD: lysergic acid; MDMA: methylenedioxymethamphetamine Source: Reference 1
Kuti15 and colleagues compared the analgesic efficacy and side effects of intramuscular (I/M) Pentazocine and Tramadol during labour analgesia and found that Pentazocine has better analgesic efficacy at sixty minutes after injection 47.
Compounds with mixed agonist and antagonist activity at opioid receptors have been synthesized and they include pentazocine (Sosegon), butorphanol (not available in Pakistan, Stadol), and buprenorphine (Temgesic), are the most commonly available drugs at the sale counter of medical stores and
Genotoxicity evaluation of morphine, buprenorphine, pentazocine and noscapine by micronucleus assay & comet assay in mice.
Adequate pain control was by intramuscular injections of pentazocine.
Opioids associated with the serotonin syndrome include meperidine, fentanyl, tramadol, and pentazocine.
Similarly, mixed agonist-antagonists like pentazocine or butorphanol (Stadol) have little use.
The list of potentially inappropriate drugs included: propoxyphene, indomethacin, pentazocine, methocarbamol, carisoprodol, oxybutynin, chlorzoxazone, metaxalone, cyclobenzaprine, flurazepam, amitriptyline, doxepin, meprobamate, lorazepam, oxazepam, alprazolam, temazepam, zolpidem, triazolain, chlordiazepoxide, diazepam, hydroxyzine, promethazine, all barbiturates (except phenobarbital), and meperidine.
We took morphine, diamorphine, cyclozine, codeine, temazepam, nitrezepam, phenobarbitone, sodium amytal dextropropoxyphene, methadone, nalbuphine, pethidine, pentazocine, buphrenorphine, dextromoramide chlormethiazole.