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Topical L-Ascorbic Acid: Percutaneous Absorption Studies.
Percutaneous absorption of parathion in vitro in porcine skin: Effects of dose, temperature, humidity, and perfusate composition on absorptive flux.
A general trend has been seen that unsaturated fatty acids are more effective in enhancing percutaneous absorption of drugs than their saturated counterparts.
Effect of vehicles and penetration enhancers on the in vitro and in vivo percutaneous absorption of methotrexate and edatrexate through hairless mouse skin.
As described above, percutaneous absorption of the drug was not high even after continuous application in the morning and at night for 5 days, suggesting hardly any safety problem.
Clinical effectiveness is influenced by chemical composition and vehicle type, which later determines differences in percutaneous absorption.
2002; Koo and Lee 2004) and that percutaneous absorption of DEP occurs (Api 2001; ATSDR 1995; Mint et al.
Animal skin, especially that of the nude mouse, has a huge amount of percutaneous absorption.
In the extensive, two-month study, Lipoderm was tested using the exacting Franz Skin Finite Dose Model, which utilized samples of human skin, in vitro, to evaluate the percutaneous absorption of four different drugs.

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