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The reason why many patients with PLS do develop periodontal inflammation is most likely due to the fact that the amount of aerobic and anaerobic pathogens in the periodontal pocket overpower a somewhat weakened innate immune response.
Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder presented with diffuse transgradient palmoplantar hyperkeratosis, and an aggressive periodontal inflammation leading to premature loss of primary and permanent teeth.
Those things we know reduce periodontal inflammation," she continued.
We was interested in emphasizing the presence of the iatrogenic factors, the periodontal modifications which appear especially in the irritation area, indexes of oral hygiene and of the periodontal inflammation degree, the appreciation of the prosthetic restoration quality comparing to the marginal periodontium, the correlation of the clinical aspects with radiographic elements (retroalveolar Xrays, OPT) for analyzing the shape, the affecting degree of the periodontium bone, and the unraveling of the ethiopathogenetic mechanisms.
The researchers found that compounds belonging to the two categories showed similar results in resolving periodontal inflammation and tissue regeneration.
Kenneth Kornman to Discuss Periodontal Inflammation and Gene-Environment Interactions