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showed that PCV compared to VCV was associated with lower peak and plateau pressures and better oxygenation indices in both prone and supine positions before and during pneumoperitoneum.
The table 13 shows the comparison between pressure controlled ventilation & volume controlled ventilation group for peak & plateau pressure at base line which reveals that a high significant difference was present in peak & plateau pressure at.
Effects of tidal volume reduction in acute lung injury (ALI) patients with inspiratory plateau pressures < 32 cmH20 before tidal volume reduction.
VL = volume loading, MABP = mean arterial blood pressure, HR = heart rate, Ppeak = airway peak pressure, Pplat = airway plateau pressure, Cstat = total static compliance of the respiratory system, ETC[.
Therefore, the current trend is to ventilate these patients with tidal volumes based on about 6 ml/kg of ideal body weight and positive end-expiratory pressure (PEEP), along with attempting to achieve plateau pressures of less than 35 cm H20.
An increase in the plateau pressure signals a fall in the global lung compliance.
Plateau pressure is needed to calculate total lung compliance as the relationship between PPLAT and delivered volume.
Despite the focus of the recent literature on airway pressure and flow based indicators (such as plateau pressure, mean airway pressure, stress index, inflection/deflection points and tidal compliance) for setting tidal volume and PEEP, it is hazardous to rely on any of these without knowing the intrapleural pressure and absolute volume of the lungs.
2], peak pressure of airway (Ppeak) and plateau pressure of airway (Pplat) were recorded at five time points: 20 minutes after TLV in the lateral position (T1), 20 minutes (T2), 40 minutes (T3) and 60 minutes (T4) after the initial of OLV and 20 minutes after conversion to TLV (T5).
To date, virtually every published clinical trial has relied on the airway plateau pressure as the primary indicator of maximum tidal stress applied to the parenchyma.
Alveolar pressure pushes both the lung and the chest wall outward, so that some percentage of the recorded plateau pressure results from the recoil of the chest wall.
On a purely mechanical level, it has been clearly shown that reducing the application frequency of high pressure tidal cycles can protect the lung, even when the same plateau pressure, mean airway pressure and PEEP are maintained.