platelet-derived growth factor
receptor-[alpha]/CEP4 amplification and increase in gene copy numbers were assessed by FISH method in all cases, and no amplification was detected.
Platelet-derived growth factor
Agostinelli et al., "Platelet-derived growth factor
alpha mediates the proliferation of peripheral T-cell lymphoma cells via an autocrine regulatory pathway," Leukemia, vol.
Steed, "Clinical evaluation of recombinant human platelet-derived growth factor
for the treatment of lower extremity ulcers," Plastic and Reconstructive Surgery, vol.
Brozowski et al., "Platelet-derived growth factor
receptor is a novel modulator of type a [gamma]-aminobutyric acid-gated ion channels," Molecular Pharmacology, vol.
Increased dermal expression of platelet-derived growth factor
receptors in growth-activated skin wounds and psoriasis, J Invest Dermatol 1991;96:983-986.
They secrete several chemokines such as epidermal growth factor (EGF), fibronectin, fibrinogen, histamine, platelet-derived growth factor
(PDGF), serotonin, and von Willebrand factor.
Also, PRP gel can be used to deliver high quantities of key growth factors, such as platelet-derived growth factor
AB (PDGF-BB), transforming growth factor [beta]-1 (TGF[beta]-1), and vascular endothelial growth factor (VEGF), and recruit repairing cells to the site of tissue damage [9,10], which are essential to natural wound healing.
The pathogenesis of PDP is not yet clearly understood; however, recently growing evidence supports that the vascular endothelial growth factor (VEGF) and platelet-derived growth factor
(PDGF) could play a central role.
(19) Of the proteins transcribed, the most important in terms of tumor angiogenesis is VEGF, a member of the platelet-derived growth factor
(18) The most commonly studied platelet proteins include platelet-derived growth factor
(PDGF), transforming growth factor (TGF-[beta]), platelet-derived epidermal growth factor (PDEGF), vascular endothelial growth factor (VEGF), insulin-like growth factor 1 (IGF-1), fibroblastic growth factor (FGF), epidermal growth factor (EGF) and cytokines including proteins such as platelet factor 4 (PF4) and CD40L.
Periodontal regeneration in class III furcation defects of beagle dogs using guided tissue regenerative therapy with platelet-derived growth factor
. J Periodontol 1995;66:462-77.