A motor dysfunction, bradykinesia, was assessed by the pole test
. Especially FE groups showed significant improvement (p<0.001), whereas the results of VE groups were similar to the MPTP group.
Therefore the main goal of the study was to investigate the protective effect of curcumin in ameliorating the rotenone-induced motor deficits by using different behavioral parameters (pole test
, kondziela inverted screen test, inclined plane test, open field test, beam walking and footprint test) and biochemical alterations in rats.
Another is pole test
, which can further assess the motor function.
For the functional assays, hyperforin treatment was associated with increased behavioural asymmetries, and significantly increased times on the rotarod and pole test
. Authors concluded the results to demonstrate that hyperforin promotes angiogenesis and functional recovery after stroke through IL-17A-mediated elevation of VEGF expression.
For the 12 studies on the motor dysfunction of MPTP-induced PD model, 2 studies [16, 17] provided clear data of rotarod test, 2 studies [22, 33] provided clear data of swim-score values, 4 studies [16, 17, 23, 39] provided graphical data of pole test
, and the other 6 studies [24, 26, 28, 29, 32, 34] were descriptive studies without any data.
The pole test
was performed one day before MPTP injection (day 0), 2 h after the fifth acupuncture stimulation (day 5), and 2 h after the last acupuncture stimulation (day 12).
. Pole tests
were performed following a previously published protocol starting on the 1st day after treatment began .
The demanding assessment includes a 64km/h frontal offset test and a 50km/h side impact test, along with a 29km/h pole test
, a whiplash test simulating a 32km/h rear-end crash, and a 40km/h pedestrian impact protection test.
The compact SUV was tested with an optional side thorax airbag, but its test results showed poor protection levels, particularly in the side pole test