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Conclusion: In Pakistani women the association of TP53 gene codon 72 arginine/proline polymorphism was present.
Genotyping of CAT-21A/T (rs7943316) gene promoter polymorphism was carried out using thermal cycler followed by RFLP.
Since ethnic variation in allele frequency is widely documented, [3,8] population specific data of VDR polymorphism has to be generated before conducting a valid genetic association study.
While Glu27Gln polymorphism did not showed significant association with nocturnal asthma both in genotype (OR =1.
sup][16] The three GSTs GSTM1, GSTT1, and GSTP1 are the predominant members of the GST family, and deletion of the gene encoding GSTM1 or GSTT1 or the polymorphism Ile105Val (rs1695) of GSTP1 can impact the binding affinity of these enzymes and/or reduce or eliminate cellular GST activity.
Restriction fragment length polymorphism, Single-nucleotide polymorphism
VDR polymorphisms may be involved in etiology of vitiligo and future studies should be design to screen large sample size for more VDR polymorphism to get more precise picture.
The statistical analysis indicated that non-significant association existed between SOD1 (rs2070424) gene polymorphism and RA (p>0.
Researchers conducted statistical studies on a cohort of more than 14,000 women of African descent and didn't find any association of the polymorphism with increased breast cancer risk overall.
A total of 249 patients with complaints of nausea and vomiting and 242 patients without nausea and vomiting were analyzed for C3435T polymorphism using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method.
7), found in American population that the frequency with the lowest prevalence for rs320 polymorphism was G allele (39%), for rs285 T allele (39%) and for rs328 Gallele (15%), the latest prevalence was used to calculate sample size, because was the lowest from the three analyzed polymorphisms.
The independent effect of each risk polymorphism and haplotypes on UL was assessed via logistic regression analysis.
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