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Pronounced activity in another prefrontal area accompanied sparse blood flow in the hippocampus and amygdala, areas responsible for consciously recalled memories and fear conditioning, respectively.
Brain imaging studies and electrical stimulation of precise spots on the brains of anesthetized humans (SN: 4/30/88, p.281) indicate the prefrontal area is crucially involved in word perception, silent and oral reading, verbal reports of memories and grammatical analysis of complex sequences of spoken words.
Most patients who were included in our study had prefrontal lesions, because we were mainly interested in precisely describing prefrontal areas involved in endogenous set shifting.
For example, a study using resting-state functional connectivity MRI found that patients with TRD showed reduced FC in bilateral prefrontal areas and the thalamus areas, while patients with TSD showed reduced FC in bilateral hippocampus, amygdale and insula.
The research findings reveal that activity in reward areas of the brain in response to pictures of appetizing food predicts whether people tend to give in to food cravings and desires in real life, whereas activity in prefrontal areas during taxing self-control tasks predicts their ability to resist tempting food.
The most consistent observation in Electro Encephalography, a graph of a person's brainwaves, in individuals with autism is a pattern of slow waves, called theta waves in the central, frontal and prefrontal areas. Slow waves may also be seen on the right temporal and the right parietal lobes.
In brain imaging studies, exposure to aggressive imagery produced greater activation in the amygdala and less activity in prefrontal areas of the brain in people with intermittent explosive disorder, compared with controls.
The team found the areas that turn off during blinking are the visual cortex, which is responsible for seeing, plus the parietal and prefrontal areas - active when a person is conscious of what is happening around them.
For the FDDNP scans, the researchers quantified regional binding in the medial and lateral temporal lobe, the parietal lobe, the frontal and prefrontal areas of the frontal lobe, and the cerebellum (the control region).