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Conclusion: Our study shows that idiopathy contributed to most of the cases of presenile cataract followed by diabetes mellitus, high myopia and smoking.
Further studies are warranted to assess the risk of presenile cataracts over the life course of older DG individuals.
The fact that carriers for various metabolic diseases such as early vascular disease in homocystinuria, hyperammonemic episodes in ornithine transcarbamylase deficiency, presenile cataracts in galactosemia, and so forth (Endres 1997), as well as for AAT deficiency (Feld 1989; Gourley et al.